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Selected Document Category:Published Document
Source:Nanotechnology Characterization Laboratory
Anticipated Publication Year:
Publication Year:2011
Acronym:NCL
Identifier:ITA-12
Document Title:Coagulation Assays
url:http://ncl.cancer.gov/NCL_Method_ITA-12.pdf
Scope:

This document describes a protocol for assessing the effect a nanoparticle formulation may have on plasma coagulation time. Coagulation, i.e, blood clotting, is a highly complex process that involves many components. There are three main pathways for coagulation: intrinsic (also
known as the contact activation pathway, because it is activated by a damaged surface); extrinsic (also known as the tissue factor pathway); and
the final common pathway. Each pathway can be assessed by a specialized test.

Keywords:APTT, TT, Coagulation
Type of Document:e. Specification
Issues Areas:Measurement and Characterizations
Health, Safety, and Environment
Primary Category:Chemicals e.g. pesticides, pharmaceuticals, paints, basic chemicals
Additional Categories
Goal or Need:
Intended Stakeholders:
Is it Being Implemented:
Submitter's Name:Admin
Submitter's e-mail:[email protected]
Submitter's Company:ANSI
Additional Comments:
Contact for Additional Info:http://ncl.cancer.gov/working_assay-cascade_download.asp



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