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Selected Document Category:	Published Document
Source:	Nanotechnology Characterization Laboratory
Anticipated Publication Year:
Publication Year:	2011
Acronym:	NCL
Identifier:	ITA-17
Document Title:	In Vitro Induction of Leukoc yte Procoagulant Activity by Nanoparticles
url:	http://ncl.cancer.gov/NCL_Method_ITA-17.pdf
Scope:	Leukocyte procoagulant activity (PCA) is accepted as an important component in the onset of disseminated intravascular coagulation (DIC). DIC is common in acute promyelocytic leukemia (APL) and other forms of cancer 1-5. DIC in cancer patients is often observed afterinitiation of therapy with cytotoxic oncology drugs that act by altering DNA replication (e.g.,doxorubicin, daunorubicin, and vincristin)3, 6.
Keywords:	PCA, DIC, APL
Type of Document:	e. Specification
Issues Areas:	Measurement and Characterizations Health, Safety, and Environment
Primary Category:	Chemicals e.g. pesticides, pharmaceuticals, paints, basic chemicals
Additional Categories
Goal or Need:
Intended Stakeholders:
Is it Being Implemented:
Submitter's Name:	Admin
Submitter's e-mail:	[email protected]
Submitter's Company:	ANSI
Additional Comments:
Contact for Additional Info:	http://ncl.cancer.gov/working_assay-cascade_download.asp

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