Selected Document Category:Published Document
Source:International Organization for Standardization
Anticipated Publication Year:
Publication Year:2014
Identifier:TR 16197
Document Title:Nanotechnologies — Compilation and description of toxicological screening methods for manufactured nanomaterials

This Technical Report provides a compilation and description of in vitro and in vivo methods that may be useful for the toxicological, including ecotoxicological, screening of engineered and manufactured nanomaterials. Toxicological screening tests included in this report can be used for such purposes as early decision-making in research and product development, rapid feedback on potential toxicological / safety concerns, or for the preliminary assessment of manufactured nanomaterials.

The report is intended to complement other international efforts that address nanomaterial toxicology by focusing on screening methods suited for preliminary assessment and is not intended to duplicate similar efforts in other international organizations such as the Organisation for Economic Cooperation and Development (OECD). If screening provides an early indication of hazard, the guidance will refer to other organizations’ approaches for full-scale toxicological assessment or further tiered studies.

Keywords:Toxicology, screening, testing, manufactured nanomaterials
Type of Document:a. Standard
Issues Areas:Health, Safety, and Environment
Primary Category:
Additional Categories
Goal or Need:This report provides information on methods that can be used to screen nanomaterials in order to: determine whether to continue development of a nanomaterial itself and/or a product containing a nanomaterial; determine whether to take on the cost of performing the remaining tiers within a complete tiered-testing strategy; or determine whether appropriate controls are in place to continue nanomaterial research in the laboratory
Intended Stakeholders:
Is it Being Implemented:
Submitter's Name:Heather Benko
Submitter's e-mail:hbenko@ansi.org
Submitter's Company:ANSI
Additional Comments:
Contact for Additional Info: