Selected Document Category:Published Document
Source:International Organization for Standardization
Anticipated Publication Year:
Publication Year:2019
Identifier:TR 22019
Document Title:Nanotechnologies - Considerations For Performing Toxicokinetic Studies With Nanomaterials

This document describes the background and principles for toxicokinetic studies relevant for nanomaterials.

Annex A shows the definitions for terminology with respect to toxicokinetics as used in OECD TG 417:2010

Keywords:nanomaterials, toxicology, risk assessment, toxicokinetics, OECD
Type of Document:a. Standard
Issues Areas:Health, Safety, and Environment
Primary Category:
Additional Categories
Goal or Need:Toxicokinetics of nanoparticles is of special interest because, in comparison to larger sized particles, the small size of free nanoparticles could enable an increased rate of translocation beyond the portal of entry, to the lymphatic fluid and blood circulation, from where they can reach other body organs. In addition, smaller sized nanoparticles may show a more widespread organ distribution than larger sized particles.
Intended Stakeholders:
Is it Being Implemented:
Submitter's Name:Heather Benko
Submitter's e-mail:hbenko@ansi.org
Submitter's Company:ANSI
Additional Comments:
Contact for Additional Info:Heather Benko, hbenko at ansi.org