Selected Document Category: | Published Document
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Source: | International Organization for Standardization
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Anticipated Publication Year: | 2020
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Publication Year: | 2021
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Acronym: | ISO
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Identifier: | TS 23034
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Document Title: | Nanotechnologies — Method to estimate cellular uptake of carbon nanomaterials using optical absorption
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url: |
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Scope: | This document describes a near-infrared optical absorption method to estimate the in vitro cellular uptake of carbon nanomaterials including both internalized and/or tightly adhered to the cell membrane from liquid dispersions. This is a simple method to screen carbon nanomaterials uptake; additional analysis using a different technique can be required if quantification is desired.
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Keywords: | carbon nanomaterials, carbon nanotubes, cellular uptake, EHS
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Type of Document: | a. Standard
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Issues Areas: | Health, Safety, and Environment
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Goal or Need: | Owing to their unusual physical and chemical properties, carbon nanomaterials (CNMs), such as carbon nanotubes, carbon black, graphene, and carbon nanohorns, have been considered for various applications such as in the fields of electronics, energy, nanotechnology, and biology. With the increase of CNM-based products on the market, the public concern regarding possible toxicities has also increased. Estimation of the amount of CNM associated with the targeted cells is useful for an initial toxicological screening of CNMs and for developing applications in medicine
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Intended Stakeholders: |
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Is it Being Implemented: |
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Submitter's Name: | Heather Benko
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Submitter's e-mail: | [email protected]
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Submitter's Company: | American National Standards Institute
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Additional Comments: |
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Contact for Additional Info: | Heather Benko, hbenko at ansi.org |