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Selected Document Category:	Published Document
Source:	International Organization for Standardization
Anticipated Publication Year:
Publication Year:	2024
Acronym:	ISO
Identifier:	4962
Document Title:	Nanotechnologies - In vitro acute nanoparticle phototoxicity assay
url:	https://webstore.ansi.org/standards/iso/iso49622024
Scope:	This document specifies a procedure to evaluate acute phototoxicity of nanoparticles (NPs), suspended in cell culture media, by measuring the relative reduction in cellular viability under near ultraviolet (UVA) exposure (315 nm to 400 nm). The measurement is intended to assess the potential for acute phototoxicity of NPs by comparing NP photoactivity in vitro to a positive control chlorpromazine. It is not designed to predict other joint effects of nanomaterials and light, such as genotoxicity, photo-allergy or photo-mutagenicity. The method is also applicable to NP aggregates and agglomerates.
Keywords:	Phototoxicity, titanium dioxide
Type of Document:	a. Standard
Issues Areas:	Health, Safety, and Environment
Primary Category:	Chemicals e.g. pesticides, pharmaceuticals, paints, basic chemicals
Additional Categories	Personal care products
Goal or Need:
Intended Stakeholders:
Is it Being Implemented:
Submitter's Name:	Heather Benko
Submitter's e-mail:	[email protected]
Submitter's Company:	ANSI
Additional Comments:
Contact for Additional Info:

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