Selected Document Category:Published Document
Source:International Organization for Standardization
Anticipated Publication Year:
Publication Year:2012
Document Title:Surface characterization of gold nanoparticles for nanomaterial specific toxicity screening: FT-IR method

This Technical Specification provides guidelines for the identification of the surface bound molecules using FT-IR of dehydrated gold nanoparticle (AuNPs) films both before and after nanomaterial (NM) cytotoxicity testing.

NOTE 1 AuNPs may have surface bound ligands prior to testing and may be additionally covered (or coated) with organic- or bio-molecules during the cytotoxicity test.

NOTE 2 Nucleic acids, amino acids, lipids or membrane components binding to AuNPs can be observed by FTIR spectroscopy by detection of absorption bands corresponding to phosphodiester, amine or lipid, respectively, although the type of nucleic acids, proteins or lipid cannot be identified in detail based on IR spectra.

Keywords:gold nanoparticles, cytotoxicity
Type of Document:a. Standard
Issues Areas:Measurement and Characterizations
Health, Safety, and Environment
Primary Category:Chemicals e.g. pesticides, pharmaceuticals, paints, basic chemicals
Additional Categories
Goal or Need:
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Is it Being Implemented:
Submitter's Name:Heather Benko
Submitter's e-mail:hbenko@ansi.org
Submitter's Company:ANSI
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