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Selected Document Category:	Published Document
Source:	International Organization for Standardization
Anticipated Publication Year:	2020
Publication Year:	2021
Acronym:	ISO
Identifier:	22455
Document Title:	Nanotechnologies - High Throughput Screening Method For Nanoparticles Toxicity Using 3D Model Cells
url:	https://webstore.ansi.org/Standards/ISO/ISOTR224552021
Scope:	This proposal is to define a reliable and repeatable high throughput screening method to evaluate the cytotoxicity of 3D cells exposed to nanoparticles. This includes methods to prepare the 3D cells and to expose the 3D cells to nanoparticles.
Keywords:	nanoparticles, cytoxicity, 3D cells, screening assays
Type of Document:	a. Standard
Issues Areas:	Health, Safety, and Environment
Primary Category:
Additional Categories
Goal or Need:	With the increase of nano-consumer using nanomaterials, the potential exposure to nanomaterials have been raised. However, there are no suitable methods to evaluate the cytotoxicity of nanoparticles based on high-throughput screening method. High-throughput approaches allow the bulk of the screening analysis for manufactured nanoparticles and high-volume data generation for nanoparticle toxicity.
Intended Stakeholders:
Is it Being Implemented:
Submitter's Name:	Heather Benko
Submitter's e-mail:	[email protected]
Submitter's Company:	ANSI
Additional Comments:
Contact for Additional Info:	Heather Benko, ISO/TC 229 WG 3 Secretary; hbenko at ansi.org

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